Wednesday, August 26, 2020

Animal Testing Research Paper Essay

As residents of the United States we are qualified for our social equality. They incorporate our essential requirements for carrying on with a cheerful and safe life. Creatures anyway are not qualified for any rights to guarantee them security, great wellbeing, and legitimate day to day environments. Creature testing research centers torment and execute guiltless creatures day by day. The research centers smell of synthetic compounds and fade, and the pens are grimy, and not appropriately kept. The shocking scents fill their noses and they are compelled to stroll in their own pee and excrement. These creatures are required to endure in these conditions day by day, this isn't empathetic, and it is a moderate and excruciating demise. Holding a guiltless creature without wanting to and tormenting them with destructive substances is creature mercilessness and ought to be unlawful; there are effective elective approaches to creature testing. Creature testing is known as the utilization of creatures in investigations and improvement activities to decide poisonousness, measurement, and viability of test tranquilizes before continuing to human clinical preliminaries (â€Å"Animal Testing†). Creature testing is such a dubious theme since it includes utilizing a living life form to test various medications and synthetic concoctions and can conceivably have a lethal result. The measure of pressure put onto the creature all through the testing is undesirable and agonizing for the creature. It is much the same as a creature being fiercely beaten by their proprietor; lamentably the medications and other pernicious substances constrained onto the creature have long haul impacts and cause the creature to endure it to see the aftereffects of the test. This is so unfeeling and wrong. Creatures ought not need to endure this inconceivable agony. There are various explanations behind creature testing, the principle ones being for restorative purposes, for example, cosmetics brands and plastic medical procedure systems like Botox. Researchers utilize the creatures to explore various medications and synthetic substances and basically are searching for anomalous responses from them. Being a female I buy diverse restorative items that I use on an everyday premise. Beauty care products are articles expected to be applied to the human body for purifying, enhancing, advancing engaging quality, or changing the appearance without influencing the body’s structure or capacities (â€Å"Fact Sheetâ€Cosmetic Testing†). The absolute most generally realized brands test their items on creatures. Organizations like Johnson and Johnson, Avon, Kleenex, Vaseline, Dove, Giorgio Armani, Maybelline, and innumerable more organizations test their items on creatures. Researchers direct skin disturbance tests that rub synthetic substa nces onto shaved skin or drop the synthetic concoctions into rabbit’s eyes with no agony medicine (â€Å"Fact Sheet-Cosmetic Testing†). They are trying items with the synthetic substances that might cause the disturbance, for example, cosmetics remover, eye shadow, mascara, and things applied to the eye or eyelid. This test is clearly insensitive and agonizing for the bunnies, yet there are options in contrast to this test are compassionate and should be possible instead of it. Rather than putting the synthetic concoctions onto the bunnies, producers can drop the synthetics onto gave human corneas (Cosmetics and Household). Ladies wear cosmetics and buy items that are applied routinely to the face and eyes. With those items I am believing that they will improve my physical highlights in a positive manner, however I would not need those items to be tried in such a merciless and unbearable way. Illnesses are another purpose behind testing on creatures. Malignancy, Down condition, heart issues, diabetes, and others are a portion of the fundamental ailments researchers are attempting to discover remedies for. The opposite side to creature testing can possibly spare lives by discovering remedies for these dangerous maladies. This is the reason a few pieces of creature testing are so imperative to our wellbeing frameworks and patients. Numerous colleges use creatures to test in various sorts of preparing programs. At the University of Michigan nursing understudies utilized a feline to work on placing a cylinder into its windpipe. The objective of the system was for attendants dealing with endurance trips to have the option to play out the methodology to patients in basic condition. The feline was later embraced into a family and was not hurt by any stretch of the imagination (Kozlowski). In spite of the fact that this specific strategy appears to be innocuous to the feline and sounds easy crusades kept on challenging utilizing live creatures and PETA kept on squeezing the subject. They needed them to supplant utilizing live creatures with test systems which for all intents and purposes does likewise (Kozlowski). Tests like this that are done appear to be so minuet contrasted with others that are utilized for discovering fixes. Creature testing for human wellbeing has been supposed to be perilous, untrustworthy, and costly. On the opposite there have been situations where creature testing for clinical reasons has in certainty discovered antibodies and fixes. From 1940 to 1960 polio was one of the most famous and notable illnesses. Due to theâ research directed on creatures polio has been disposed of as a notable illness due to an immunization that nearly everybody has gotten (Use of Animals). Today kids get a lifetime antibody for polio and are additionally inoculated against typhus, challenging hack, and lockjaw. I can see where the debate comes in. I certainly think discovering solutions for every one of these sicknesses are something that should be done, and yet creatures ought to have rights to their bodies. Creatures that are constrained into these offices to be tried on originate from every unique piece of the world. Uncommonly reproduced rodents and mice are the warm blooded creatures utilized in most clinical examination (â€Å"What Types of Animals†). Different warm blooded creatures regularly found in research are guinea pigs, bunnies, hamsters, and livestock, for example, pigs and sheep (â€Å"What Types of Animals†). Now and again it has been reputed that a portion of the creatures are uniquely reared for particular sorts of testing. This has brought up a great deal of issues with respect to how exact the tests really are. Various creatures are utilized for specific tests. In past examinations it was demonstrated that specific creatures respond diversely to similar tests. This is the reason such huge numbers of various varieties and sorts of creatures are influenced by this; it includes such a large number of various supplies and hardware which thusly can turn out to be expensive. Creature testing has been known to be an expensive and a dishonest method of finding exact fixes. A few tests can take months or even a very long time to lead and break down. This can bring about burning through several thousands, once in a while even a huge number of dollars on one test (â€Å"Costs of Animal†). The wastefulness and over the top expenses related with creature testing makes it incomprehensible for controllers to satisfactorily assess the likely impacts of in excess of 100,000 synthetic concoctions around the world (â€Å"Costs of Animal†).The measure of time expected to lead one basic test is excessively outrageous. The creature is languishing over months to years, for one outcome that isn’t even ensured. The measure of cash spent on one test isn’t justified, despite all the trouble, when the outcomes are not generally exact. Elective testing can spare numerous creature lives; they additionally are more affordable and set aside less effort to finish. The non-creature techniques are increasingly powerful and in particular, progressively moral. Organizations should utilize advanced PC innovation for testing and medication improvement. Innovation has becomeâ the most significant thing in the public eye; it gives researchers the instruments to expand human capacities, so why are organizations declining to utilize the innovation that is introduced in the public arena? These strategic approaches on tormenting creatures are against business morals. Populace considers have demonstrated what number of irresistible ailments are caused and furthermore what number of can be forestalled. Truth be told, the National Insitutes of Health announced that in excess of 80 HIV/AIDS antibodies that have passed creature testing have flopped in clinical preliminaries (â€Å"Alternatives: Testing without Torture†). Non-creature tests are another extraordinary other option. Non-creature tests incorporate an early stage undeveloped cell test, 3T3 impartial red take-up photograph poisonousness tests and human skin extra from surgeries (â€Å"Alternatives: Testing without Torture†). There are such a large number of options in contrast to creature testing that ought to be used as opposed to utilizing live creatures. Then again creature testing has added to finding a wide range of fixes and medicines for various maladies. Regardless of anything else if you’re cherished one has a malady and the best way to locate a compelling fix is to test it on a creature, at that point you would need it done. Last chance assumes an immense job in why such a large number of individuals bolster creature testing. Creatures are the best thing to test on the grounds that they share indistinguishable qualities from people. Chimpanzees share 99% of their DNA with people, and mice are 98% hereditarily like people (Animal Testing-ProCon). Imparting DNA to a creature has such a large number of constructive outcomes; the likeliness of finding a fix from testing on one of these creatures could spare such a large number of lives. Laws have directed creature testing to keep the pitiless and unbearable acts from occurring (Animal Testing-ProCon). There are numerous positive sides to creature testing that might profit our wellbeing frameworks and patients. Creature Cruelty is illicit in many states in the U.S. How is tormenting creatures, jabbing them with needles, scouring destructive synthetic substances onto their bodies and at them lawful? It is characterized as something very similar. Holding an honest creature without wanting to and tormenting them with hurtful substances is creature brutality and ought to be unlawful. There are certain options in contrast to discovering fixes and medicines. Despite the fact that there are a few positives, the measure of cash, time, and creature cold-bloodedness isn't justified, despite any potential benefits, considering the outcomes are not generally exact. The measures of stressâ they are gotten through in these labs are sufficient to execute them without the medications. The affliction and torment of these blameless creatures are not worth ensuring our mascara doesn’t mak

Saturday, August 22, 2020

Industry Analysis: Banking Essay example -- Essays Papers

Industry Analysis: Banking The financial business has gone under expanding cynicism recently due to increasing short and long haul loan fees. The financial business' market capitalization made a generous decrease. Most speculators are worried about whether the business can support proceeded with productivity because of these elements. Banks have reacted lately to these issues by expanding endlessly from premium touchy items and administrations. However, loan fees are the central part of any money related administrations. In this manner, I accept the money related administrations industry will be profoundly influenced by increasing loan costs. Banks have encountered great business factors in the course of recent years. Loan costs were low, credit quality was acceptable, and expansion was low. These components are generally prescient of the kinds of profit banks should report. Be that as it may, great occasions can't proceed on the grounds that loan fee climbs cause diminished loaning movement, harmed credit quality, and decreased estimations of bond portfolios. Doorman's Five Forces Analysis: 1. Rivalry among contending merchants: The financial business is proceeding to rebuild and situate itself for our changing economy subsequently, numerous uber mergers have happened as of late. Citicorp and Travelers Insurance consented to converge in April 1998 at an estimation of $70 billion. Bank of America and Nation's Bank likewise consented to combine without further ado a short time later which turned into the biggest bank in the United States. Bank merg...

Friday, August 14, 2020

How the Dopamine Works With Partial Agonism

How the Dopamine Works With Partial Agonism Schizophrenia Print How Antipyschotic Dopamine Works With Partial Agonism By Adrian Preda, MD Medically reviewed by Medically reviewed by Steven Gans, MD on August 05, 2016 Steven Gans, MD is board-certified in psychiatry and is an active supervisor, teacher, and mentor at Massachusetts General Hospital. Learn about our Medical Review Board Steven Gans, MD Updated on January 31, 2020 More in Disorders Schizophrenia Addiction ADHD Eating Disorders Social Anxiety Disorder Bipolar Disorder BPD Depression OCD GAD Panic Disorder PTSD View All In this article, you will learn about dopamine partial agonism. This effect is best illustrated by aripiprazole (brand name: Abilify), a second-generation antipsychotic/atypical neuroleptic that stands apart from all the other atypical antipsychotics due do a different mechanism of action. How Aripiprazole Is Different From Other Atypicals Most atypical antipsychotics have a clear effect of the brain serotonin receptors but a rather weak and limited effect on the brain dopamine receptors. Aripiprazole is different than most of the other atypicals with regards to its mechanism of action. In essence, aripiprazole works via dopamine. Thus, from the point of view of it works, aripiprazole is closer to typical or first-generation neuroleptics, which share the blocking of dopamine in the brain (so-called dopamine antagonism) as a common mechanism of action. If Aripiprazole Works on Dopamine Why is it Classified as an Atypical? The reason is aripiprazole’s clinical action: its risk for certain neurological adverse effects such as episodes of acute muscular rigidity (dystonia) or involuntary abnormal movement disorders (dyskinesia) is low, which earns it accolades as an atypical; as opposed to antipsychotics with a high risk for this type of adverse effects, which are classified as typicals. Aripiprazole is a dopamine partial agonist as opposed to a dopamine antagonist or blocker like most first-generation antipsychotics. Dopamine Antagonism Dopamine is one of the neurotransmitters found at the level of the synaptic space, space in-between neurons. Dopamine is released in the synaptic space from vesicles housed in the pre-synaptic neuron, then binds to dopamine receptors at the level of the postsynaptic neuron. Think of this as a key and lock type of effect where dopamine receptors are locks which open when the dopamine “key” enters the lock. One of the hypotheses of schizophrenia is that in certain parts of the brain there is too much dopamine in the synapse. The positive symptoms  of schizophrenia are thought to be a result of all these “extra” dopamine molecules binding to dopamine receptors. Dopamine antagonists bind to the dopamine receptors, thus block dopamine binding. And without the proper key, i.e. dopamine, the lock does not open; in other words, as the dopamine excess problem is corrected at the level of the synapse there are no ill effects (positive symptoms) resulting from it. The problem though is that the dopamine blockade occurs all over the brain while the dopamine excess in schizophrenia is limited to specific parts of the brain. Further, in schizophrenia, while some parts of the brain are subject to dopamine excess, other parts are in fact experiencing a dopamine deficit. Dopamine antagonists do not only block receptors in places where there is too much of it but also in places where there is not enough dopamine. This is why these medications, while effective for positive symptoms due to blocking of receptors in brain regions having too much dopamine, tend to also increase negative symptoms, cognitive issues, as well as the risk for parkinsonism in patients taking them, due to blocking of dopamine in brain regions where there is too little dopamine. A potential solution to this problem is using partial agonists. Partial Dopamine Agonists A partial dopamine agonist is a molecule that binds to the receptor and partially activates it. Think about it as a key that sorts of fit in the lock so that the door can be wriggled about but not completely open. The effect of a partial dopamine agonist is less than the full effect of dopamine but more than a complete lack of effect, which is what happens when a receptor is completely blocked. In other words, a partial effect. This partial effect means that when there is too much dopamine around aripiprazole (a partial dopamine agonist) by taking the dopamine space on the receptors and activating them only partially will actually take down the effect of the too much dopamine. It also means that in situations when there is too little dopamine around to activate all the available receptors aripiprazole will actually bind to unoccupied receptors and its effect, even if only partial, is now added to the dopamine effect in the synapse for a net increase of the dopaminergic effect of a dopamine-deprived synapse. To summarize, aripiprazole, as a partial dopamine agonist, acts as a modulator of dopamine effects. When present, it diminishes the effects of both dopamine excess (by decreasing dopamine action when there is too much of it) and deficit (by increasing dopamine action when there is too little of it).

Sunday, May 24, 2020

Of Mice and Men by John Steinbeck - 613 Words

Some characters in this novel are alienated by mainstream society because they do not fit society’s ideal image of a person. And they are all not accepted as human beings. Throughout John Steinbeck’s novel, Of Mice and Men, the social injustice of how people were treated during the Great Depression is explored through the characters Crooks, Curley’s wife, and Lennie, to show that society actually needs to become stronger than it really is. The character Crooks is not accepted due to the fact that he is an African American male in a white dominated society. The ranch owner has Crooks segregated from the rest of the workers, and in his own separate room. All of the people treat him unfairly by the things they say to him just because of the color of his skin. Referring to Crooks as the n-word quite often, they only see this situation from their point of view. â€Å"‘Sure. Ya see the stable buck’s a nigger’† (20). Because of these character istics of Crooks he is lower than the typical man in society. Crooks also does not fit society’s ideal image of a person because he is also handicap. When Crooks was younger he was kicked in the back by a horse, and now he has a crooked back. â€Å"‘Got a crooked back where a horse kicked him’† (20). One night, when George and all the other guys went out to town, they left Lennie behind at the barn with the puppies. Later on, Lennie found his way into Crooks’ bedroom in the back of the barn. Of course it was different at first, and they did not seemShow MoreRelatedOf Mice and Men by John Steinbeck973 Words   |  4 PagesIntroduction: I. Background A. John Steinbeck was born on February 27th, 1902 in Salinas, California. 1. Salinas River was one of the few centers for shipping, farming, and agriculture a. John Steinbeck worked as an employed laborer, digging canals and working beside men similar to characters in his novels. 2. In a discussion John Steinbeck said, I worked in the same country that the story is laid in. The characters are composites to a certain extent. Lennie was a real person. Hes in an insaneRead MoreOf Mice and Men, by John Steinbeck842 Words   |  4 Pages it was not uncommon to become morosely secluded while working. Men would go far away from their families in search of any jobs they could get, with only themselves to confide in; colleagues only filling in the void of friends and family partially. Naturally, John Steinbeck’s novel Of Mice and Men, written during this period, would reflect this fact as a major aspect of the story. Loneliness would become the sinew of Of Mice and Men, manifested in some of the story’s main characters: Candy, CrooksRead MoreOf Mice and Men by John Steinbeck1358 Words   |  6 Pagesthis expression to stress the fact that there are and will be difficulties in life. John Steinbeck, in his novella Of Mice and Men, does not fall short of the same views. It takes place in the year 1937, a period associated with the Great Depression, and illustrates the hardships of the time, and more so those that laborers such as George and Lennie experience. Life proves to be full of disappointments for both men who are victims of harsh circumstances in more ways than one. The two have a dreamRead MoreThe And Of Mice And Men By John Steinbeck1549 Words   |  7 PagesThis essay will be exploring the role of women in the texts ‘DNA’ by Dennis Kelly and ‘Of Mice and Men’ by John Steinbeck. Both texts are quite dissimilar for the most part, with ‘DNA’ being a contemporary play, dealing with problems faced by modern youth groups and ‘Of Mice and Men’ being a classic novella. Set in the 1930’s, the novella tells a story of two migrant workers who flee to Salinas, California, for work. In spite of this, both explore the presentation of female characters similarlyRead MoreOf Mi ce And Men By John Steinbeck894 Words   |  4 PagesOf Mice and Men Essay John Steinbeck once said, â€Å"A journey is a person in itself; no two are alike. And all plans, safeguards, policing, and coercion are fruitless. We find that after years of struggle that we do not take a trip; a trip takes us†. In his novella, Of Mice and Men, two men go on an unexpected journey in search for their dream of happiness. There are many themes that come from their journey such as, the gilded American dream, the bond of male friendships, the power of women and femininityRead MoreOf Mice And Men By John Steinbeck1433 Words   |  6 PagesI am writing a literary essay on the novella, Of Mice and Men by John Steinbeck. I will be responding to the question describe an important character and explain how the character helped you understand an important message. In the novella, Of Mice and Men, written by John Steinbeck, two characters, Crooks and Curley’s wife, help me understand the message ‘Discrimination isolates people’. The book takes place in Soledad, California, mid 1930’s, during the Great Depression, at a time when discriminationRead MoreOf Mice And Men By John Steinbeck1747 Words   |  7 Pages Of Mice and Men is a tragedy And The Pearl is a parable. Author s Name John Steinbeck -Title of Work #1: Of Mice and Men -Genre: Tragedy -Evidence of Genre (explain what makes the work an example of the genre): Tragedy is a branch of literature that uses a serious and dignified style the sad or unfortunate events encountered or caused by a heroic individual. In Of Mice and Men George and Lennie face a lot of tragic events. -Complete Summary of Work: Of Mice and Men is theRead MoreOf Mice And Men By John Steinbeck1354 Words   |  6 PagesThe novel ‘Of Mice and Men’, written by John Steinbeck, is set near the Salinas River in California, America during the Great Depression between 1930-1939. The Great Depression was a distressing time in the history of America as the unemployment rate was high which in turn led to poverty and hunger. During this time, many struggled to find work and this steered them to travel long distances, often without having anyone to talk to. Dreams were crafted by this travelling workforce and were somethingRead MoreMice Of Men By John Steinbeck785 Words   |  4 Pages It was an hopeless time period. For George in steinbeck s book mice of men by John Steinbeck,it was the great depression.This was a time period of a deep and dark economic downturn that affected the whole country. While the story focuses on George and Lennie s struggles through this hopeless time.They were best buds that got along great. They went to farm to farm as migrant works to get there pay. George had to take care of Lennie throughout the book and pick up the pieces, but lennie was a kindRead MoreOf Mice And Men By John Steinbeck1400 Words   |  6 PagesOf Mice and Men, it is not just a band! Of Mice and Men was originally a short novel written by John Steinbeck in the 1930s. Regardless of the shortness in length, though, it is a rather deep and emotional book with quite a few messages behind the fictional storyline. These messages, however, cannot be discovered right off the bat. To genuinely absorb the messages Steinbeck teaches and actually understand the meaning behind them, one must read the book in its entirety. Steinbeck educates readers

Wednesday, May 13, 2020

What Is Source Code in Computer Programming

Source  code is the list of human-readable instructions that a programmer writes—often in a word processing program—when he is developing a program. The source code is run through a  compiler  to turn it into machine code, also called object code, that a computer can understand and execute. Object code consists primarily of 1s and 0s, so it isnt human-readable.   Source Code Example Source code and object code are the before and after states of a computer program that is compiled. Programming languages that compile their code include C, C, Delphi, Swift, Fortran, Haskell, Pascal and many others. Here is an example of C  language source code: /* Hello World program */#includestdio.hmain(){printf(Hello World)} You dont have to be a computer programmer to tell that this code has something to do with printing Hello World. Of course, most source code is much more complex than this example. It is not unusual for software programs to have millions of lines of code. Windows 10 operating system is reported to have about 50 million lines of code. Source Code Licensing Source code can be either proprietary or open. Many companies closely guard their source code. Users can use the compiled code, but they cannot see or modify it. Microsoft Office is an example of proprietary source code. Other companies post their code on the internet where it is free to anyone to download. Apache OpenOffice is an example of open source software code. Interpreted Program Languages Code Some programming languages such as JavaScript are not compiled into machine code but are  interpreted  instead. In these cases, the distinction between source code and object code does not apply because there is only one code. That single code is the source code, and it can be read and copied. In some cases, developers of this code may intentionally encrypt it to prevent viewing. Programming languages that are interpreted include Python, Java, Ruby, Perl, PHP, Postscript, VBScript and many others.

Wednesday, May 6, 2020

At Risk Students Free Essays

Below is a list of warning signs that an educator may see with these types of abuses. Warning Signs of Potential Abuse: Be aggressive, oppositional, or defiant * Act out, displaying aggressive or disruptive behavior * Fear of going home * Be described as â€Å"accident prone† * Being a low achiever * Showing regressive or less mature behavior * Dislike or shrink from physical contact These are just a few of the signs that are listed as â€Å"Behavioral Clues That May Indicate Child Abuse† (Cross-Tower, 2003, Para. ), since bruises are not always a sure indicator of abuse. We will write a custom essay sample on At Risk Students or any similar topic only for you Order Now Warning Signs of Potential Drug Abuse: * Withdrawal * Isolation Fatigue Depression * Aggressive Rebellious Behavior * Change in Friends * Drop in Academic Performance These are a few of the signs that In an article by Bowers (2013) and according to him, â€Å"[m]ore than one of these behavioral changes must be present In the student for a substantial amount of time before an assumption is made by a teacher about drug use† (up. 2). Warning Signs of Suicidal Tendencies: * Loss of interest in activities previously enjoyed * â€Å"Acting out† verbally or physically, at home or at school * Preoccupation with death and dying * Loss of Interest or participation In school life Sudden reports of trouble at school * Difficulty concentrating These are a few signs that could indicate, â€Å"[p]attention signs of suicidal feelings and Houghton† (Boson’s Children Hospital, 2013, Para. 18); however, these could also be signs of depression. Moreover, a teacher should see assistance If these signs appear If one of my students had any of these signs, I would be concerned. The first thing I would do is my research and find out what the protocols are when reporting suspicions of child mistreatment or abuse. Secondly, in these cases I wouldn’t second guess myself and I would report my suspicions to the appropriate authority, in addition, I would indicate that these are suspicions and that I do not know for sure if abuse is occurring. Furthermore I would do was talk to the child to see if they are willing to disclose what is going on with him or her. If the child discloses anything, I will add that to my suspicions when I turn in my report to the proper authorities. I will continue to keep a watchful eye on the student, and if anything else occurs after I make my report, I will turn that information in as well. Next, I will follow the progress that is going on in the case and ask for any updates available. Moreover, my main priority at all times is my student’s well-being and I will continue to report each case f abuse I witness because it is my responsibility to ensure my student’s safety and well-being when he or she is in my care. How to cite At Risk Students, Papers

Sunday, May 3, 2020

Importance Of Culture In Business Samples †MyAssignmenthelp.com

Question: Discuss about the Importance Of Culture In Business. Answer: Introduction What is culture? Culture, in simple words, can be defined as the difference of thoughts, beliefs, religion, ethnicity, language, cuisines, etc. that exists between individuals and groups. The behavior of a person in a social setup is an attribute of his or her cultural values or the culture to which he or she belongs. Importance of culture in business The spread of globalization has brought some drastic changes in the business world. Companies from all over the world are now trying to expand their operations in new markets that can offer them an increased potential and are also establishing cross border connections with other business organizations. In cross border communications, culture plays an important role as people belonging to different countries have different cultural backgrounds and their behavior can be a factor of their cultural values. While communicating with people from different cultural backgrounds, it is important to have knowledge about their culture because what is normal in a persons culture, it might be offensive to the other person. As a result, the spread of globalization has brought around a need to attain cultural knowledge while planning to communicate across borders. Cross cultural management cultural differences between Australia and Japan Japan is a country that is located in East Asia and has an estimated population of 126,740,000. The country has a GDP (Gross Domestic Product) of $5.420 Trillion as of 2017 and is the third largest economy in the world. On the other hand, Australia is a country that is located on Oceania and has an estimated population of 24,676,900. The country had a GDP of $1.189 Trillion in 2016 and is considered to be a wealthy country. The two countries carry out a lot of business with each other as their policies and status compliments each other. During 2015-16, Japan was Australias third largest partner in terms of trade as Japan is the second largest export market for Australia. Australia too imports goods from Japans, such a passenger vehicles, refined petroleum, goods vehicles and gold (Department of Foreign Affairs and Trade , 2017). Hofstedes cultural dimensions Named after the proposer of the theory Geert Hofstede the Hofstedes cultural dimension theory is a work that aims at getting a better understanding of cross cultural communication. In his theory, he used certain cultural dimensions to study the effect of culture on the behavior of a society (Hofstede, 2011). These cultural dimensions are power distance, individualism, masculinity, uncertainty avoidance, long-term orientation and indulgence. A comparison of Japans and Australias culture on the basis of Hofstedes cultural dimension is given below: Power distance Australia scores 36 on this dimension while Japan has a score of 54 on the power distance index. This implies that the Japanese are more concerned about their position in the organizational hierarchy as compared to the Australians (Hofstede-Insights, n.d.). Individualism Australia scores 90 on the individualism index whereas Japan has a score of 46. This implies that in the Japanese society, people like to be a part of a collective society. On the other hand, the Australian culture scores very high on individualism and has a very loosely knit society (Frost, 2013). The Australians look after themselves and the employees are expected to be self-reliant. Masculinity Australia scores 61 on the masculinity index while Japan has a very high score of 95 in this index. According to the Australian culture, achievements and success are an important part of life and most of the hiring or promotion decisions are based on them. On the other hand, Japan is one of the most masculine societies in the world. The competition between individuals is severe in the Japanese culture and they compete with one another in all walks of life. Uncertainty avoidance Australia scores 51 on the uncertainty avoidance index while Japan has a high score of 92. Japan, with a score of 92, is one of the most uncertainty avoiding countries in the world. Japan has been subjected to a number of natural and man-made disasters in the past and this very fact has forced the country to become peculiar about each and everything that they do (Advantagepartnershipexecutivesearch, n.d.). As a result, they avoid uncertainties as much as they can. On the other hand, Australia scores an intermediate score of 51 on this scale. Long-term orientation Australia has a score of 21 on the long-term orientation index while Japan has a score of 88. Japan is a society that believes in basing its decisions on long-term goals and objectives rather than aiming for short-term goals or objectives. On the other hand, Australia has a normative culture and have a greater need for quick results. Indulgence Australia is considered to be an indulgent country with a score of 71 while Japan scores 42 when it comes to indulgence. The Australians have a higher willingness to realize their impulses and desires and like to indulge in fun loving activities (Radford, et al., 1993). On the other hand, Japan with a score of 42 has a culture where the people show a restrain towards their impulses and desires. Cultural and communication challenges between Australia and Japan As discussed above, Australia and Japan conduct a lot of business with each other despite a large difference between their cultural values. The cultural differences between the two countries can be clearly observed by comparing them using Hofstedes cultural dimensions. Therefore, it is important for business organizations, belonging to both the countries, to have a complete knowledge about each others cultural values so that they can communicate with each other without misunderstandings or unintentionally offending each other. Some important things, with respect to culture, that an Australian must keep in mind while doing business with a Japanese entity are discussed below: First of all, one of the major cultural issue that an Australian is likely going to face, while getting into business with a Japanese, is related with the language differences. Japanese speak English better on phone than in person. A Japanese employee would try to avoid communicating in English during face-to-face conversation because of his or fear to make a blunder and lose reputation (Lay, 2006). As a result, an Australian must keep it in mind that there will be a linguistic difference between the two of them. Secondly, for an Australian to build effective relations with his Japanese counterpart, it is important for him to act with integrity, demonstrate exceptional listening skills and show verbal expressiveness as these are some of the traits that can easily impress a Japanese person. Furthermore, the Japanese society prefers face-to-face communication over other modes of communication. Japanese have a tendency to perceive written material, visual aids, graphs, pictures, etc. as offensive and unfriendly. On the other hand, the Australians have a tendency to adopt tones during communication and use written or graphical material for communicating their idea in a better way. Thus, an Australian can offend a Japanese if he or she is unaware about this cultural difference. Thirdly, when in Japan, the Japanese have a tendency to make offers for things and utilities that they think are important and might be required by their guest. On the other hand, a guest demanding something from the Japanese can offend a Japanese person as they do not consider it to be polite. Therefore, an Australian dealing with a Japanese must not demand anything from him or her, until they offer it themselves. Fourthly, it is evident from the Hofstedes cultural dimension model, Japan is a country that believes that power is highly distributed in the society and believes in a system of hierarchy. In Japan, the performance of the employees is evaluated by their seniors and it is not considered to be wise to leave the office before the superiors leave. On the other hand, Australians do not believe much in power distribution and attach a great importance to work-life balance. For Australians, leaving before their superior will not be a big deal. Furthermore, age is considered to be a definition of a persons seniority in the Japanese culture. For an Australian, it is important to treat Japanese elders differently than the way in which he or she would deal with the younger ones (Martinuzzi, n.d.). Therefore, Australians should keep that in mind that they have to respect the power or the position that a Japanese holds in his organization hierarchy while communication or dealing with him. Fifthly, Japan is a country that tends to avoid uncertainties as much as they can. Before taking a firm decision, they are more likely to analyze even the minutest details of the deal. On the other hand, the Australians have a higher tendency to avoid uncertainties. Therefore, an Australian carrying out business with his or her Japanese counterpart must be patient while negotiating with them as they can take time to finalize their decision. Sixthly, Japanese preferences during communication can greatly vary as compared to that of an Australian. In Japanese, it is a common saying that hear one, understand ten (Kopp, 2012). Japanese believe that during a conversation, if 10% of the information is expressed verbally then the remaining 90% of the conversation is communicated through non-verbal communication and should be understood by the other party. On the other hand, Australians are very particular about the information that they share in their conversation and might demand more details from their Japanese counterparts. Seventhly, privacy is very important in Japanese culture. The Japanese like to maintain their privacy and are reserved in nature. Therefore, for an Australian, who wants to do business with a Japanese, it is very important to avoid getting into personal details in the beginning phase of establishing a relation because the Japanese are such private people that they can even get their names removed from another persons phonebook if they want. Eighthly, the Japanese culture is a high context culture i.e. they place more value to the information that is shared through non-verbal cues, such as body language, eye contact, behavior, etc. whereas the Australian culture is a low context culture i.e. they place more value to information shared through written documents, contracts, etc. Therefore, an Australian must keep it in mind that his non-verbal cues are being perceived by his Japanese counterpart and an unintentional move might end up offending the Japanese person. Lastly, meetings for the Japanese are not what the Australians might think it is. In Australian culture, a maximum of two to three people can be sent for a meeting if themanagement feels that they have acquired all the information that they should (Friedman, 2014). For Japanese, a meeting is an opportunity to collect information and they can send as many as 20 people for a meeting. Thus, the Australians should consider this fact and keep it in mind. Recommendations/Conclusion There are a significant number of differences between Australia and Japan, which can make business dealing difficult between an Australian and a Japanese. An Australian who wants to establish effective business relations with a Japanese should definitely study the Japanese culture in detail and learn their preferences, communication patterns, mannerism, etc. before starting to build a relation because relations really matter in the Japanese culture and it can become difficult for an Australian to establish effective relations if he or she is not aware about the Japanese culture. References Department of Foreign Affairs and Trade , 2017. Japan country brief. [Online] Available at: https://dfat.gov.au/geo/japan/pages/japan-country-brief.aspx[Accessed 10 October 2017]. Hofstede-Insights, n.d. COUNTRY COMPARISON. [Online] Available at: https://www.hofstede-insights.com/country-comparison/australia,japan/[Accessed 9 October 2017]. Frost, A., 2013. Japanese Culture and Hofstedes Five Dimensions. [Online] Available at: https://restaurantkyoto.dk/blog/en/japanese-culture/[Accessed 10 October 2017].management Advantagepartnershipexecutivesearch, n.d. Cultural Differences between Australia and Japan. [Online] Available at: https://www.advantagepartnershipexecutivesearch.net/26871c9c-9d3e-4437-939c d8cc9626829f.html[Accessed 10 October 2017]. Radford, M. H., Mann, L., Ohta, Y. Nakane, Y., 1993. Differences between Australian and Japanese Students in Decisional Self-Esteem, Decisional Stress, and Coping Styles. Journal of Cross-Cultural Psychology , 1 September. Hofstede, G., 2011. Dimensionalizing Cultures: The Hofstede Model in Context. Online Readings in Psychology and Culture, 2(1). Lay, G. C. C., 2006. The Influences of Culture on Differences in Australian and Japanese Communicative Behavior and Work Styles, s.l.: s.n. Kopp, R., 2012. Articles of Interest. [Online] Available at: https://www.japanintercultural.com/en/news/default.aspx?newsid=204[Accessed 10 October 2017]. Martinuzzi, B., n.d. DOING BUSINESS IN JAPAN: 10 ETIQUETTE RULES YOU SHOULD KNOW. [Online] Available at: https://www.americanexpress.com/us/small-business/openforum/articles/doing-business-in-japan-10-etiquette-rules-you-should-know/ [Accessed 10 October 2017]. Friedman, S., 2014. 6 Things You Need To Know About Doing Business In Japan. [Online] Available at: https://www.businessinsider.com/6-things-to-know-about-business-in-japan-2014-6?IR=T[Accessed 10 October 2017].